Winter: A grueling season for dry and sensitive skin.
Cold winds trigger immediate redness; cleansing leaves the face feeling tight and stripped. The skin barrier acts like a “drafty wall”—while you attempt to hydrate on one side, moisture is rapidly escaping from the other.
How can dry and sensitive skin survive the winter smoothly?
Evonik’s all-new Water-Soluble Ceramide, SKINLIPIX® HydraShield, steps into the arena!
SKINLIPIX® HydraShield: Product Profile
INCI Name: Ceramide NP; Ceramide NG; Sorbitol; Water; Betaine; Polyglyceryl-10 Stearate; Polyglyceryl-6 Behenate
Appearance:
Raw Material
1% & 3% Aqueous Solution:

Technological Background: Deep Eutectic Solvent (DES) Technology × Innovative NATUCERA® Process
Solved Application Pain Points: Cold processable; Water-dispersible.
Key Claims: Dual “Ceramide” nourishing combination (Ceramide NP & Ceramide NG); Barrier protection derived from vegetable oil-based ceramides and moisturizing factors.
Mechanisms of Action:
Repairs the “Drafty Wall” (Barrier reinforcement)
Locks in “Escaping Water” (Occlusion)
Binds “Thirsty Water” (Humectancy)
Transports “Deep Water” (Aquaporin activation)
Awards: 2025 Ringier Technology Innovation Award
Recommended Dosage: 1.5% – 5%
Beyond the profile, let’s take a deep dive into this high-performance debut.
First and foremost, SKINLIPIX® HydraShield is backed by the industry giant Evonik. Even before its launch, it had a precise mission: To solve the formulation application barriers of traditional ceramides!
Innovation: Water-Soluble, Cold Processable Ceramide
The Challenge:
Traditional ceramide products typically require high-temperature dissolution in oil during formulation and are prone to crystallization, creating significant challenges for formulators.
The Solution:
Evonik’s R&D team developed an innovative solution using Deep Eutectic Solvent (DES) technology.
- Technology: Sorbitol and Betaine act as a deep eutectic solvent to stabilize 2.25% Ceramide NP & Ceramide NG, while simultaneously functioning as humectants.
- Bio-Mimetic: Sourced from olive oil, this dual-ceramide combination precisely matches the lipid structure of human skin, enhancing absorption efficiency and barrier repair.
- Ease of Use: The product exists as a stable liquid, allowing for cold processing and direct dispersion in water, drastically simplifying formulation complexity.
Dual-Source Nourishment, Multi-Dimensional Hydration
Solving formulation issues is just the beginning. What truly distinguishes SKINLIPIX® HydraShield is its visualized efficacy in layer-by-layer moisture locking, making it a savior for dry, sensitive skin.
The Concept:
A healthy skin barrier is a solid wall, defending against pollutants, microbes, and chemical irritants while selectively allowing beneficial ingredients in.
In contrast, dry/sensitive skin has a “drafty” barrier. Weakened defense leads to redness from external irritants, while excessive Transepidermal Water Loss (TEWL) causes dryness, tightness, fine lines, and roughness.
SKINLIPIX® HydraShield Action Mechanism:
- Repairs the “Leaking Wall”: Increases Ceramide content.
- Locks “Escaping Water”: Boosts Tight Junction proteins to prevent moisture loss.
- Binds “Thirsty Water”: Delivers moisturizing components.
- Transports “Deep Water”: Activates Aquaporins to increase water retention.
Scientific Validation (Ex Vivo Study):
Immunofluorescence staining studies on human skin explants evaluated the effect of SKINLIPIX® HydraShield on key markers for dry skin: Aquaporin-3, Tight Junction proteins, and Ceramides.
Results:
- Tight Junction Protein (Claudin-1): Increased by 71%, significantly strengthening the internal skin barrier and effectively retaining water.
- Aquaporin-3 (AQP3): Increased by 37%, improving skin hydration channels.
- Ceramide Content: Increased by 40%, ensuring effective delivery to the stratum corneum.



Barrier Repair: Resisting External Penetration
Ex Vivo Penetration Test:
Simulating the penetration of irritants from the outside in, the study showed:
- 1.5% Concentration: Achieved 20% barrier repair effect.
- 5% Concentration: Achieved 35% barrier repair effect, restoring barrier defense capabilities.

Clinical Testing: Immediate & Long-Term Hydration
SKINLIPIX® HydraShield delivers both instant hydration and sustained moisturizing effects.
1. Immediate Hydration
Within 2 hours of application, skin surface (stratum corneum) hydration levels significantly improved, demonstrating immediate efficacy.

2. Long-Term Moisturizing (Face & Legs)
Face: After 28 days, skin hydration imaging showed lighter colors in the SKINLIPIX® HydraShield group, indicating higher hydration levels. Notably, the moisturizing effect persisted 5 days after stopping usage.
Legs: Using the same methodology, deep grey color scales indicated superior skin hydration status.


3. Texture Improvement
Continuous use resulted in a visible improvement in skin texture on both the face and legs.

Formulation Applications
To demonstrate the unique water-soluble properties of SKINLIPIX® HydraShield, BioHope (Distributor) has developed two prototype formulations:
1. Golden Radiance Softening Lotion
Appearance: Semi-transparent / Translucent.
Advantage: 1% SKINLIPIX® HydraShield shows excellent stability with other water-soluble actives. It can be added after cooling to 45°C with simple stirring—no pre-dissolution required.
2. Crystal Clear Ceramide Shampoo
Appearance: Transparent.
Advantage: Even at 1.5% concentration in a high-surfactant system, the formula remains completely transparent and stable.
Interested in learning more?
For detailed product specifications, formulation guidelines, or to request samples, please contact us via email at LONGWAY!

